PXD039297

PXD039297 is an original dataset announced via ProteomeXchange.

Title	Systematic comparative analysis of extracellular vesicles following apoptosis, necroptosis and ferroptosis
Description	The formation of extracellular vesicles (EVs) has emerged as a novel paradigm in cell-to-cell communication during health and disease. According to the type of cell death modalities, the intercellular functions of EVs may be influenced by their biogenesis and composition. To identify a possible EV cargo signature, we performed a comparative analysis of steady-state (ssEVs) and cell death-associated EVs (cdEVs) following apoptosis (apoEVs), necroptosis (necEVs) and ferroptosis (ferEVs) in the same cell type. We determined the physical and biochemical characteristics, the protein cargo by mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:05:54.110.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sara Dufour
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-01-05 21:53:23	ID requested
1	2023-10-12 05:29:40	announced
⏵ 2	2023-11-14 09:05:55	announced	2023-11-14: Updated project metadata.

Cappe B, Vadi M, Sack E, Wacheul L, Verstraeten B, Dufour S, Franck J, Xie W, Impens F, Hendrix A, Lafontaine DLJ, Vandenabeele P, Riquet FB, Systematic compositional analysis of exosomal extracellular vesicles produced by cells undergoing apoptosis, necroptosis and ferroptosis. J Extracell Vesicles, 12(10):e12365(2023) [pubmed]

submitter keyword: necroptosis,extracellular vesicles, ferroptosis, apoptosis, cell death

Peter Vandenabeele
contact affiliation	Molecular Signaling and Cell Death Unit, VIB Center for Inflammation Research, Ghent, Belgium. Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
contact email	peter.vandenabeele@irc.vib-ugent.be
lab head
Sara Dufour
contact affiliation	VIB-UGent
contact email	sara.dufour@vib-ugent.be
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD039297

PRIDE project URI

• PRIDE
  1. PXD039297
     1. Label: PRIDE project
     2. Name: Systematic comparative analysis of extracellular vesicles following apoptosis, necroptosis and ferroptosis