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PXD039296

PXD039296 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome analysis of neonatal mouse brain and brain capillaries
DescriptionThe functions and protein expressions of the blood-brain barrier are changed during brain development after birth. The purpose of the present study was to develop a method to isolate brain capillaries from a single frozen neonatal mouse brain and elucidate the enrichment of brain capillaries by quantitative proteomic analysis. The brain capillary fraction was prepared by the optimized method from a single frozen mouse neonatal brain (postnatal day 7). The brain capillary fractions and brain lysates were digested by trypsin and analyzed by DIA.
HostingRepositoryjPOST
AnnounceDate2023-07-12
AnnouncementXMLSubmission_2024-03-27_06:55:53.085.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSumio Ohtsuki
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; O-phospho-L-serine; O-phospho-L-threonine
Instrumentinstrument
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-01-05 18:21:25ID requested
12023-07-11 08:00:30announced
22024-03-27 06:55:54announced2024-03-27: Updated PubMed.
Publication List
Hamada Y, Ogata S, Masuda T, Ito S, Ohtsuki S, Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries. Fluids Barriers CNS, 20(1):50(2023) [pubmed]
Keyword List
submitter keyword: mouse, brain, brain capillary, DIA
Contact List
Sumio Ohtsuki
lab head
Sumio Ohtsuki
contact affiliationKumamoto University
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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