PXD039210

PXD039210 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Differences in Aqueous Humor Protein Profiles in Patients With Proliferative Diabetic Retinopathy Before and After Aflibercept Treatment
Description	To investigate the changes in aqueous humor (AH) protein profiles before and after intravitreal aflibercept (IVA) treatment in patients with proliferative diabetic retinopathy (PDR) patients. 5 PDR patients provided 10 samples of AH before and after IVA treatment (pre-group vs post-group). Proteins were identified using liquid chromatography-tandem mass spectrometry. Then, bioinformatics was employed to investigate the functional significance of differentially expressed proteins (DEPs) and hub proteins.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:40:18.158.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tan Wang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-01-03 00:59:25	ID requested
1	2024-05-21 11:24:03	announced
⏵ 2	2024-10-22 06:40:19	announced	2024-10-22: Updated project metadata.

Publication List

10.1186/s12886-024-03292-1;
Wang T, Chen H, Du X, Bintao Qiu MM, Li N, Min H, Differences in aqueous humor protein profiles in patients with proliferative diabetic retinopathy before and after aflibercept treatment. BMC Ophthalmol, 24(1):32(2024) [pubmed]

10.1186/s12886-024-03292-1;

Wang T, Chen H, Du X, Bintao Qiu MM, Li N, Min H, Differences in aqueous humor protein profiles in patients with proliferative diabetic retinopathy before and after aflibercept treatment. BMC Ophthalmol, 24(1):32(2024) [pubmed]

Keyword List

submitter keyword: proteomics, aflibercept,proliferative diabetic retinopathy, LC-MS/MS

submitter keyword: proteomics, aflibercept,proliferative diabetic retinopathy, LC-MS/MS

Contact List

Hanyi Min
contact affiliation	Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College
contact email	minhy@pumch.cn
lab head
Tan Wang
contact affiliation	8618595929325
contact email	drwangtan@126.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD039210
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD039210

PRIDE project URI

Repository Record List

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