PXD039207

PXD039207 is an original dataset announced via ProteomeXchange.

Title	Identification of the novel progression factors in renal cell carcinoma through global proteomics
Description	Renal cell carcinoma (RCC) is among the top 8 most diagnosed cancer in United States, which 79,000 patients newly were diagnosed and 13,920 deaths [1]. The clear-cell RCC (ccRCC) is the most common histopathological subtype representing approximately 85~90% in all diagnosed case [2]. In renal cancer treatment, metastasis is considered the most serious problem. Metastatic RCC (mRCC) is a fetal disease. It is known that about 25~30% of patients diagnosed with early kidney cancer have metastasized [3, 4]. The 5-year survival rate of patients with mRCC is 11.7%, and the prognosis is very poor [5]. Approximately 30% of patients have recurrence despite removal of the primary tumor, including 10-15% of patients found in T1 and clinically removed [4]. The mRCC patients show poor response to chemotherapy and radiotherapy, the rate of disappointing for treatment is increased from 15% to 25% [6, 7]. The common sites of RCC metastasis is known to the lung (40%), bone (30%), lymph node (22%) and liver (20%) [8].
HostingRepository	PRIDE
AnnounceDate	2024-01-30
AnnouncementXML	Submission_2024-01-29_23:02:27.694.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ann-Yae Na
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2023-01-03 00:56:06	ID requested
⏵ 1	2024-01-29 23:02:28	announced

Park J, Lee EH, Sim H, Na AY, Choi SY, Chung JW, Ha YS, Kwon TG, Lee S, Lee JN, Using Comparative Proteomics to Identify Protein Signatures in Clear Cell Renal Cell Carcinoma. Cancer Genomics Proteomics, 20(6):592-601(2023) [pubmed]

10.21873/cgp.20408;

submitter keyword: Human,Renal carcinoma cell

Sangkyu Lee
contact affiliation	Kyungpook national university
contact email	pharm239@gmail.com
lab head
Ann-Yae Na
contact affiliation	kyungpook national university
contact email	cpblady@hanmail.net
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD039207

PRIDE project URI

• PRIDE
  1. PXD039207
     1. Label: PRIDE project
     2. Name: Identification of the novel progression factors in renal cell carcinoma through global proteomics