PXD039178

PXD039178 is an original dataset announced via ProteomeXchange.

Title	Identification of myosin heavy chain post-translational modifications in patients with MHY mutations
Description	Congenital myopathies are rare genetic muscle diseases notably due to mutations in the MYH2 gene. Here we assessed their myosin heavy chain post-translational modifications. For that, we purified beta/slow and type IIa myosin heavy chains from limb muscles of five patients and five healthy controls. We then ran a LC/MS analysis.
HostingRepository	PRIDE
AnnounceDate	2023-01-30
AnnouncementXML	Submission_2023-01-30_02:19:46.346.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	MichaelWierer
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2023-01-02 19:10:38	ID requested
⏵ 1	2023-01-30 02:19:46	announced

Dataset with its publication pending

submitter keyword: myosin, MHY,PTM

JulienOchala
contact affiliation	Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
contact email	julien.ochala@sund.ku.dk
lab head
MichaelWierer
contact affiliation	Proteomics Research Infrastructure, University of Copenhagen
contact email	michael.wierer@sund.ku.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/01/PXD039178

PRIDE project URI

• PRIDE
  1. PXD039178
     1. Label: PRIDE project
     2. Name: Identification of myosin heavy chain post-translational modifications in patients with MHY mutations