PXD039113

PXD039113 is an original dataset announced via ProteomeXchange.

Title	Quantitative phosphosproteomics revealed substrate diversity of AMPK in response to DNA damage and its crosstalk with histone acetylation in cell apoptosis
Description	AMPK is a conservative energy sensor that plays roles in diverse cellular processes via direct phosphorylation on various substrates. Emerging studies have demonstrated the regulatory roles of AMPK in DNA damages, but the underlying mechesiams remains to be fully understood. Our studies provided a source to study the phosphorylation and histone acetylation underlying the regulatory network of AMPK, which might be beneficial to understand the exact role of AMPK in DNA damage response.
HostingRepository	iProX
AnnounceDate	2022-12-29
AnnouncementXML	Submission_2023-03-02_19:28:10.152.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xiaoji Cong
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-12-29 18:58:54	ID requested
1	2022-12-29 18:59:06	announced
⏵ 2	2023-03-02 19:28:12	announced	2023-03-02: Update publication information.

Jiang Y, Cong X, Jiang S, Dong Y, Zhao L, Zang Y, Tan M, Li J, Phosphoproteomics Reveals the AMPK Substrate Network in Response to DNA Damage and Histone Acetylation. Genomics Proteomics Bioinformatics, 20(4):597-613(2022) [pubmed]

submitter keyword: Phosphoproteomics, AMPK, Proteomics

Minjia Tan
contact affiliation	Shanghai Institute of Materia Medica
contact email	mjtan@simm.ac.cn
lab head
Xiaoji Cong
contact affiliation	Shanghai Institute of Materia Medica
contact email	congxiaoji@qq.com
dataset submitter

iProX dataset URI