PXD039110
PXD039110 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | IL-33 stabilizes the transcription factor IRF1 |
| Description | Interleukin-33 (IL-33) functions both as a secreted cytokine and as a nuclear factor, with pleiotropic roles in tumor growth and immunity. Here, we explored its role in hepatocellular carcinoma (HCC) and identified that its nuclear function mediated a mechanism of immune escape. |
| HostingRepository | iProX |
| AnnounceDate | 2022-12-28 |
| AnnouncementXML | Submission_2024-02-03_20:35:33.274.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Zengbin Wang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2022-12-28 17:47:51 | ID requested | |
| ⏵ 1 | 2024-02-03 20:35:34 | announced |
Publication List
| Wang Z, Pan B, Qiu J, Zhang X, Ke X, Shen S, Wu X, Yao Y, Tang N, SUMOylated IL-33 in the nucleus stabilizes the transcription factor IRF1 in hepatocellular carcinoma cells to promote immune escape. Sci Signal, 16(776):eabq3362(2023) [pubmed] |
Keyword List
| submitter keyword: IL-33, IRF1,SUMOylated |
Contact List
| Zengbin Wang | |
|---|---|
| contact affiliation | Fujian Medical University |
| contact email | wangzengbin@fjmu.edu.cn |
| lab head | |
| Zengbin Wang | |
| contact affiliation | Fujian Medical University |
| contact email | wangzengbin@fjmu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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