PXD039067 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | TSN-interacting proteins in macrophages |
Description | TSN, a small molecular compound, was covalently attached to agarose beads via ketone or OH group. Macrophages-derived cell lysates were incubated with these TSN-conjugated beads and mass spectrometry-based proteomic analysis was performed to identify potential TSN interacting proteins |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:42:09.483.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD039067 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Fan Yang |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-12-22 02:28:33 | ID requested | |
1 | 2024-05-24 01:00:19 | announced | |
⏵ 2 | 2024-10-22 06:42:15 | announced | 2024-10-22: Updated project metadata. |
Publication List
Yang F, Zhang D, Jiang H, Ye J, Zhang L, Bagley SJ, Winkler J, Gong Y, Fan Y, Small-molecule toosendanin reverses macrophage-mediated immunosuppression to overcome glioblastoma resistance to immunotherapy. Sci Transl Med, 15(683):eabq3558(2023) [pubmed] |
10.1126/scitranslmed.abq3558; |
10.6019/PXD039067; |
Keyword List
submitter keyword: Toosendanin |
macrophages |
proteomics |
targets |
Contact List
Yi Fan |
contact affiliation | Department of Radiation Oncology, Univerisity of Pennsylvania |
contact email | yi.fan@pennmedicine.upenn.edu |
lab head | |
Fan Yang |
contact affiliation | University of Pennsylvania |
contact email | fanyangforever@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD039067 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD039067
- Label: PRIDE project
- Name: TSN-interacting proteins in macrophages