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PXD039067

PXD039067 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTSN-interacting proteins in macrophages
DescriptionTSN, a small molecular compound, was covalently attached to agarose beads via ketone or OH group. Macrophages-derived cell lysates were incubated with these TSN-conjugated beads and mass spectrometry-based proteomic analysis was performed to identify potential TSN interacting proteins
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:42:09.483.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD039067
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterFan Yang
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-12-22 02:28:33ID requested
12024-05-24 01:00:19announced
22024-10-22 06:42:15announced2024-10-22: Updated project metadata.
Publication List
Yang F, Zhang D, Jiang H, Ye J, Zhang L, Bagley SJ, Winkler J, Gong Y, Fan Y, Small-molecule toosendanin reverses macrophage-mediated immunosuppression to overcome glioblastoma resistance to immunotherapy. Sci Transl Med, 15(683):eabq3558(2023) [pubmed]
10.1126/scitranslmed.abq3558;
10.6019/PXD039067;
Keyword List
submitter keyword: Toosendanin
macrophages
proteomics
targets
Contact List
Yi Fan
contact affiliationDepartment of Radiation Oncology, Univerisity of Pennsylvania
contact emailyi.fan@pennmedicine.upenn.edu
lab head
Fan Yang
contact affiliationUniversity of Pennsylvania
contact emailfanyangforever@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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