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PXD039031

PXD039031 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe identification of ubiquitination sites of IBTK by shotgun proteomics
DescriptionPrevious study reported that eIF4A1 protein stability is subject to control by the ubiquitin-proteasome pathway, and deubiquitinase USP9X elevated eIF4A1 protein level by promoting eIF4A1 deubiquitination. However, the E3 ubiquitin ligases responsible for eIF4A1 proteolysis is not determined. Our research suggested that IBTK mediated non-degradative ubiquitination of eIF4A1, thus probable ubiquitination sites of eIF4A1 were identified by MS analysis.
HostingRepositoryPRIDE
AnnounceDate2024-05-10
AnnouncementXMLSubmission_2024-05-10_07:06:43.407.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHuiru Sun
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListubiquitination signature dipeptidyl lysine
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-12-21 05:06:05ID requested
12024-05-10 07:06:43announced
Publication List
10.7554/ELIFE.92236.2;
Keyword List
submitter keyword: IBTK, ubiquitination, shotgun
Contact List
Chenji Wang
contact affiliationGenetics Department, college of Life Sciences, Fudan University, China
contact emailchenjiwang@fudan.edu.cn
lab head
Huiru Sun
contact affiliationFudan University
contact email21112030011@m.fudan.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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