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PXD038962

PXD038962 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePyrophosphoproteomics on NOLC1 / TCOF1 / IWS1 pulldown samples
DescriptionKnown pyrophosphorylation substrates NOLC1, TCOF1, IWS1 were overexpressed in IP6K1-/- double KO HEK293T cells, along with active WT or kinase-dead IP6K1 i.e. background high or low in inositol pyrophosphates. the three proteins were pulled down via their SFB-tag and submitted to a pyrophosphoproteomics workflow. This was to demonstrate the dependence of pyrophosphorylation on PP-InsPs.
HostingRepositoryjPOST
AnnounceDate2024-03-12
AnnouncementXMLSubmission_2024-03-12_07:33:55.956.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDorothea Fiedler
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine; L-methionine sulfoxide; 2-pyrrolidone-5-carboxylic acid (Gln); unknown modification; unknown modification
InstrumentOrbitrap Fusion ETD
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-12-20 02:07:25ID requested
12024-03-12 07:33:56announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: non-canonical phosphorylation, PTM, inositol pyrophosphate, pyrophosphorylation, IP6K1
Contact List
Dorothea Fiedler, Rashna Bhandari
lab head
Dorothea Fiedler
contact affiliationLeibniz Institut für Molekulare Pharmakologie, Berlin
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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