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PXD038880

PXD038880 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSystematic profiling of lysine lactylation proteome reveals distinct changes in lactylation between the parental AGS cells and cisplatin-resistant AGS cells
DescriptionLactate enable to cause a novel post-translational modification, lactylation of proteins. We are interested in exploring whether lactate modulates DNA-damaging agents resistance in the form of lactylation. To gain a global view of DNA-damaging agents resistance-related lactylation, especially Kla of nonhistone substrates, we used 4D-Label free high-resolution LC-MS/MS, quantitative lysine lactylation analysis to investigate Kla substrates in cisplatin-resistant AGS cells.
HostingRepositoryiProX
AnnounceDate2022-12-16
AnnouncementXMLSubmission_2022-12-18_17:26:44.211.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHengxing Chen
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-12-18 17:26:19ID requested
⏵ 12022-12-18 17:26:44announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Lysine lactylation
Contact List
Hengxing Chen
contact affiliationSun Yat-sen University
contact emailchenhx49@mail2.sysu.edu.cn
lab head
Hengxing Chen
contact affiliationSun Yat-sen University
contact emailchenhx49@mail2.sysu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI

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