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PXD038849

PXD038849 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComplementarity Determining Regions in SARS-CoV-2 hybrid immunity
DescriptionPre-vaccination SARS-CoV-2 infection can boost protection elicited by COVID-19 vaccination and post-vaccination breakthrough SARS-CoV-2 infection can boost existing immunity conferred by COVID-19 vaccination. Such ‘hybrid immunity’ is effective against SARS-CoV-2 variants. In order to understand ‘hybrid immunity’ at the molecular level we studied the complementarity determining regions (CDR) of anti-RBD (receptor binding domain) antibodies isolated from individuals with ‘hybrid immunity’ as well as from ‘naive’ (notSARS-CoV-2 infected) vaccinated individuals. CDR analysis was done by liquid chromatography/mass spectrometry-mass spectrometry.
HostingRepositoryPRIDE
AnnounceDate2023-02-08
AnnouncementXMLSubmission_2023-02-08_03:18:08.787.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD038849
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterDoreenDillaerts
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-12-14 22:06:45ID requested
12023-02-08 03:18:09announced
Publication List
10.6019/PXD038849;
Keyword List
ProteomeXchange project tag: Sars-cov-2, Covid-19
submitter keyword: Human, CDR, COVID 19
Contact List
XavierBossuyt
contact affiliationKU Leuven
contact emailxavier.bossuyt@uzleuven.be
lab head
DoreenDillaerts
contact affiliationKU Leuven
contact emaildoreen.dillaerts@kuleuven.be
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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