PXD038845
PXD038845 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | KMT2A rearranged B lineage infant ALL cell line SEM treated with bortezomib LC-MS/MS |
Description | The KMT2A rearranged B lineage infant ALL cell line SEM was treated with the proteasome inhibitor bortezomib followed by a multiplexed mass spectrometry-based proteomic analysis at multiple time points (0, 6, 12, 16, and 20 hours) over 20 hours to further understand the cellular response of these cells to proteasome inhibition. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:28:46.401.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Vishwajeeth Pagala |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-12-14 22:04:30 | ID requested | |
1 | 2023-02-15 12:06:46 | announced | |
⏵ 2 | 2023-11-14 08:28:47 | announced | 2023-11-14: Updated project metadata. |
Publication List
Kamens JL, Nance S, Koss C, Xu B, Cotton A, Lam JW, Garfinkle EAR, Nallagatla P, Smith AMR, Mitchell S, Ma J, Currier D, Wright WC, Kavdia K, Pagala VR, Kim W, Wallace LM, Cho JH, Fan Y, Seth A, Twarog N, Choi JK, Obeng EA, Hatley ME, Metzger ML, Inaba H, Jeha S, Rubnitz JE, Peng J, Chen T, Shelat AA, Guy RK, Gruber TA, Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia. Nat Commun, 14(1):809(2023) [pubmed] |
Keyword List
submitter keyword: Human, Acute Leukemia, Blood, B cell, Spectrum counting |
Contact List
Tanja A. Gruber | |
---|---|
contact affiliation | Member, Stanford Cancer Institute |
contact email | tagruber@stanford.edu |
lab head | |
Vishwajeeth Pagala | |
contact affiliation | St. Jude Children's Research Hospital |
contact email | vishwajeeth.pagala@stjude.org |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD038845 |
PRIDE project URI |
Repository Record List
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