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PXD038845

PXD038845 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleKMT2A rearranged B lineage infant ALL cell line SEM treated with bortezomib LC-MS/MS
DescriptionThe KMT2A rearranged B lineage infant ALL cell line SEM was treated with the proteasome inhibitor bortezomib followed by a multiplexed mass spectrometry-based proteomic analysis at multiple time points (0, 6, 12, 16, and 20 hours) over 20 hours to further understand the cellular response of these cells to proteasome inhibition.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:28:46.401.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterVishwajeeth Pagala
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-12-14 22:04:30ID requested
12023-02-15 12:06:46announced
22023-11-14 08:28:47announced2023-11-14: Updated project metadata.
Publication List
Kamens JL, Nance S, Koss C, Xu B, Cotton A, Lam JW, Garfinkle EAR, Nallagatla P, Smith AMR, Mitchell S, Ma J, Currier D, Wright WC, Kavdia K, Pagala VR, Kim W, Wallace LM, Cho JH, Fan Y, Seth A, Twarog N, Choi JK, Obeng EA, Hatley ME, Metzger ML, Inaba H, Jeha S, Rubnitz JE, Peng J, Chen T, Shelat AA, Guy RK, Gruber TA, Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia. Nat Commun, 14(1):809(2023) [pubmed]
Keyword List
submitter keyword: Human, Acute Leukemia, Blood, B cell, Spectrum counting
Contact List
Tanja A. Gruber
contact affiliationMember, Stanford Cancer Institute
contact emailtagruber@stanford.edu
lab head
Vishwajeeth Pagala
contact affiliationSt. Jude Children's Research Hospital
contact emailvishwajeeth.pagala@stjude.org
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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