PXD038776

PXD038776 is an original dataset announced via ProteomeXchange.

Title	Quantitative LC-MS/MS Proteomics of human liver microsomes (healthy controls and normal-tumour from cancer patients)
Description	We report quantification of proteins in human liver microsomal samples from 15 healthy volunteers and 18 patients with cancer in the liver (mainly, colorectal cancer liver metastasis). These data can be used in physiologically based pharmacokinetic models to predict appropriate drug doses in patients with cancer in their liver, especially colorectal cancer liver metastasis.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:47:44.772.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Areti-Maria Vasilogianni
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-12-12 22:54:37	ID requested
1	2023-05-10 14:59:44	announced
⏵ 2	2023-11-14 08:47:46	announced	2023-11-14: Updated project metadata.

Vasilogianni AM, Al-Majdoub ZM, Achour B, Peters SA, Rostami-Hodjegan A, Barber J, Proteomic quantification of receptor tyrosine kinases involved in the development and progression of colorectal cancer liver metastasis. Front Oncol, 13():1010563(2023) [pubmed]

submitter keyword: Human, healthy controls and normal-tumour livers from cancer patients, quantitative proteomics, LC-MS/MS

Jill Barber
contact affiliation	Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, Stopford Building, Room 2.026, Oxford Road, Manchester, M13 9PT.
contact email	jill.barber@manchester.ac.uk
lab head
Areti-Maria Vasilogianni
contact affiliation	University of Manchester
contact email	aretimaria.vasilogianni@manchester.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD038776

PRIDE project URI

• PRIDE
  1. PXD038776
     1. Label: PRIDE project
     2. Name: Quantitative LC-MS/MS Proteomics of human liver microsomes (healthy controls and normal-tumour from cancer patients)