PXD038705

PXD038705 is an original dataset announced via ProteomeXchange.

Title	The interacted proteins of ALKBH5 and FTO identified by IP-mass
Description	Since m6A demethylases (FTO and ALKBH5) have been reported to be involved in pre-mRNA splicing regulation, we hypothesized that dynamic m6A distribution during mRNA maturation might involve removal of m6A in internal exons by FTO or ALKBH5 accompanied by splicing factors. To explore this we performed pull-down assays coupled with protein mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2022-12-09
AnnouncementXML	Submission_2022-12-09_15:44:10.924.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD038705
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	xinyang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2022-12-08 16:47:56	ID requested
⏵ 1	2022-12-09 15:44:11	announced

10.6019/PXD038705;

submitter keyword: ALKBH5, binding proteins, FTO

Richard I.Gregory
contact affiliation	Boston Children's Hospital
contact email	richard.gregory@enders.tch.harvard.edu
lab head
xinyang
contact affiliation	Boston Children's Hospital
contact email	Xin.Yang@childrens.harvard.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/12/PXD038705

PRIDE project URI

• PRIDE
  1. PXD038705
     1. Label: PRIDE project
     2. Name: The interacted proteins of ALKBH5 and FTO identified by IP-mass