PXD038684

PXD038684 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer
Description	TMT-MS of whole cell lysate collected from 22Rv1 castration-resistant prostate cancer cells treated with 5 µM JG-98 for 4 hours.
HostingRepository	jPOST
AnnounceDate	2023-04-25
AnnouncementXML	Submission_2023-04-26_17:39:40.881.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Frank Echtenkamp
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT; TMT; L-methionine sulfoxide
Instrument	Orbitrap Exploris 240

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-12-08 12:55:05	ID requested
1	2023-04-25 07:57:05	announced
2	2023-04-25 07:58:10	announced	2023-04-25: Updated PubMed.
⏵ 3	2023-04-26 17:39:41	announced	2023-04-27: Updated PubMed.

Publication List

Echtenkamp FJ, Ishida R, Rivera-Marquez GM, Maisiak M, Johnson OT, Shrimp JH, Sinha A, Ralph SJ, Nisbet I, Cherukuri MK, Gestwicki JE, Neckers LM, Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer. PNAS Nexus, 2(4):pgad115(2023) [pubmed]

Echtenkamp FJ, Ishida R, Rivera-Marquez GM, Maisiak M, Johnson OT, Shrimp JH, Sinha A, Ralph SJ, Nisbet I, Cherukuri MK, Gestwicki JE, Neckers LM, Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer. PNAS Nexus, 2(4):pgad115(2023) [pubmed]

Keyword List

submitter keyword: Prostate cancer, Hsp70, HspA9, mitoribosome, JG-98

submitter keyword: Prostate cancer, Hsp70, HspA9, mitoribosome, JG-98

Contact List

Leonard M. Neckers
lab head
Frank Echtenkamp
contact affiliation	NIH
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001943/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001943/