PXD038684
PXD038684 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer |
Description | TMT-MS of whole cell lysate collected from 22Rv1 castration-resistant prostate cancer cells treated with 5 µM JG-98 for 4 hours. |
HostingRepository | jPOST |
AnnounceDate | 2023-04-25 |
AnnouncementXML | Submission_2023-04-26_17:39:40.881.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Frank Echtenkamp |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | TMT; TMT; L-methionine sulfoxide |
Instrument | Orbitrap Exploris 240 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-12-08 12:55:05 | ID requested | |
1 | 2023-04-25 07:57:05 | announced | |
2 | 2023-04-25 07:58:10 | announced | 2023-04-25: Updated PubMed. |
⏵ 3 | 2023-04-26 17:39:41 | announced | 2023-04-27: Updated PubMed. |
Publication List
Echtenkamp FJ, Ishida R, Rivera-Marquez GM, Maisiak M, Johnson OT, Shrimp JH, Sinha A, Ralph SJ, Nisbet I, Cherukuri MK, Gestwicki JE, Neckers LM, Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer. PNAS Nexus, 2(4):pgad115(2023) [pubmed] |
Keyword List
submitter keyword: Prostate cancer, Hsp70, HspA9, mitoribosome, JG-98 |
Contact List
Leonard M. Neckers | |
---|---|
lab head | |
Frank Echtenkamp | |
contact affiliation | NIH |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001943/ |