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PXD038684

PXD038684 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer
DescriptionTMT-MS of whole cell lysate collected from 22Rv1 castration-resistant prostate cancer cells treated with 5 µM JG-98 for 4 hours.
HostingRepositoryjPOST
AnnounceDate2023-04-25
AnnouncementXMLSubmission_2023-04-26_17:39:40.881.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFrank Echtenkamp
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListTMT; TMT; L-methionine sulfoxide
InstrumentOrbitrap Exploris 240
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-12-08 12:55:05ID requested
12023-04-25 07:57:05announced
22023-04-25 07:58:10announced2023-04-25: Updated PubMed.
32023-04-26 17:39:41announced2023-04-27: Updated PubMed.
Publication List
Echtenkamp FJ, Ishida R, Rivera-Marquez GM, Maisiak M, Johnson OT, Shrimp JH, Sinha A, Ralph SJ, Nisbet I, Cherukuri MK, Gestwicki JE, Neckers LM, Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer. PNAS Nexus, 2(4):pgad115(2023) [pubmed]
Keyword List
submitter keyword: Prostate cancer, Hsp70, HspA9, mitoribosome, JG-98
Contact List
Leonard M. Neckers
lab head
Frank Echtenkamp
contact affiliationNIH
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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