PXD038640 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel (XL-MS) |
Description | We used chemical crosslinking mass spectrometry to study the organization and the interaction of the bovine rod outer segment cyclic nugleotide-gated channel with calmodulin. The aims of the study were to identify the D-helix that could not be resolved with cryo-EM and gain further insights into the protein organization. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:44:38.727.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Dina Schuster |
SpeciesList | scientific name: Bos taurus (Bovine); NCBI TaxID: 9913; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-12-07 07:20:12 | ID requested | |
1 | 2023-04-06 00:33:06 | announced | |
⏵ 2 | 2023-11-14 08:44:39 | announced | 2023-11-14: Updated project metadata. |
Publication List
Barret DCA, Schuster D, Rodrigues MJ, Leitner A, Picotti P, Schertler GFX, Kaupp UB, Korkhov VM, Marino J, Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel. Proc Natl Acad Sci U S A, 120(15):e2300309120(2023) [pubmed] |
Keyword List
submitter keyword: crosslinking mass spectrometry, structural proteomics, XL-MS |
Contact List
Volodymyr M. Korkhov |
contact affiliation | aboratory of Biomolecular Research, Paul Scherrer Institute, Villigen, Switzerland. Institute of Molecular Biology and Biophysics, ETH Zurich, Zurich, Switzerland. |
contact email | volodymyr.korkhov@psi.ch |
lab head | |
Dina Schuster |
contact affiliation | ETH Zurich |
contact email | dschuster@ethz.ch |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/04/PXD038640 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD038640
- Label: PRIDE project
- Name: Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel (XL-MS)