PXD038640

PXD038640 is an original dataset announced via ProteomeXchange.

Title	Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel (XL-MS)
Description	We used chemical crosslinking mass spectrometry to study the organization and the interaction of the bovine rod outer segment cyclic nugleotide-gated channel with calmodulin. The aims of the study were to identify the D-helix that could not be resolved with cryo-EM and gain further insights into the protein organization.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:44:38.727.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dina Schuster
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2022-12-07 07:20:12	ID requested
1	2023-04-06 00:33:06	announced
⏵ 2	2023-11-14 08:44:39	announced	2023-11-14: Updated project metadata.

Barret DCA, Schuster D, Rodrigues MJ, Leitner A, Picotti P, Schertler GFX, Kaupp UB, Korkhov VM, Marino J, Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel. Proc Natl Acad Sci U S A, 120(15):e2300309120(2023) [pubmed]

submitter keyword: crosslinking mass spectrometry, structural proteomics, XL-MS

Volodymyr M. Korkhov
contact affiliation	aboratory of Biomolecular Research, Paul Scherrer Institute, Villigen, Switzerland. Institute of Molecular Biology and Biophysics, ETH Zurich, Zurich, Switzerland.
contact email	volodymyr.korkhov@psi.ch
lab head
Dina Schuster
contact affiliation	ETH Zurich
contact email	dschuster@ethz.ch
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/04/PXD038640

PRIDE project URI

• PRIDE
  1. PXD038640
     1. Label: PRIDE project
     2. Name: Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel (XL-MS)