PXD038573

PXD038573 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	HDX-MS of alpha-synuclein oligomers
Description	Here we have used HDX-MS to investigate the change in structure/dynamics in synuclein oligomers formed under different conditions.
HostingRepository	PRIDE
AnnounceDate	2024-05-24
AnnouncementXML	Submission_2024-05-24_01:32:25.161.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Antonio Calabrese
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Synapt MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-12-06 02:58:30	ID requested
⏵ 1	2024-05-24 01:32:25	announced

Publication List

10.1021/jacs.4c02262;
Santos J, Cuellar J, Pallar, è, s I, Byrd EJ, Lends A, Moro F, Abdul-Shukkoor MB, Pujols J, Velasco-Carneros L, Sobott F, Otzen DE, Calabrese AN, Muga A, Pedersen JS, Loquet A, Valpuesta JM, Radford SE, Ventura S, -Synuclein Oligomer-to-Fibril Conversion. J Am Chem Soc, 146(18):12702-12711(2024) [pubmed]

10.1021/jacs.4c02262;

Santos J, Cuellar J, Pallar, è, s I, Byrd EJ, Lends A, Moro F, Abdul-Shukkoor MB, Pujols J, Velasco-Carneros L, Sobott F, Otzen DE, Calabrese AN, Muga A, Pedersen JS, Loquet A, Valpuesta JM, Radford SE, Ventura S, -Synuclein Oligomer-to-Fibril Conversion. J Am Chem Soc, 146(18):12702-12711(2024) [pubmed]

Keyword List

submitter keyword: synuclein, amyloid, oligomer,HDX

submitter keyword: synuclein, amyloid, oligomer,HDX

Contact List

Sheena Radford
contact affiliation	Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom
contact email	s.e.radford@leeds.ac.uk
lab head
Antonio Calabrese
contact affiliation	School of Molecular and Cellular Biology, University of Leeds
contact email	a.calabrese@leeds.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD038573
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD038573

PRIDE project URI

Repository Record List

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