PXD038555 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Magnetic Transferrin Assay (MTA) as a novel approach for discovering serum exosome derived protein biomarkers in neurological diseases |
Description | We developed TF-based MNPs (TF-MNPs) to isolate blood-derived exosome in this study and isolated the blood-derived exosomes of patients with neuroinflammatory diseases, such as dementia, Parkinson’s disease and multiple sclerosis via this strategy and then evaluated the proteomic profiling of these exosomes to screen for a potential candidate biomarker. Blood was collected from 10 patients in each of the three disease groups. Over 800 serum exosome proteins were identified by highly sensitive nanoflow liquid chromatography-tandem mass spectrometry (LC−MS/MS). |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:29:18.091.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Hee-Sung Ahn |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-12-05 06:25:31 | ID requested | |
1 | 2023-02-19 17:23:02 | announced | |
⏵ 2 | 2023-11-14 08:29:20 | announced | 2023-11-14: Updated project metadata. |
Publication List
Jang YO, Ahn HS, Dao TNT, Hong J, Shin W, Lim YM, Chung SJ, Lee JH, Liu H, Koo B, Kim MG, Kim K, Lee EJ, Shin Y, Magnetic transferrin nanoparticles (MTNs) assay as a novel isolation approach for exosomal biomarkers in neurological diseases. Biomater Res, 27(1):12(2023) [pubmed] |
Keyword List
submitter keyword: Human, Serum exosome, LC-MSMS, Dementia, Multiple sclerosis, Parkinson, Neurological disease |
Contact List
Kyunggon Kim |
contact affiliation | Department of Convergence Medicine, Convergence Medicine Research Center/Biomedical Research Center, Asan Medical Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea. |
contact email | kkkon1@amc.seoul.kr |
lab head | |
Hee-Sung Ahn |
contact affiliation | Asan Medical Center |
contact email | zaulim3@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD038555
- Label: PRIDE project
- Name: Magnetic Transferrin Assay (MTA) as a novel approach for discovering serum exosome derived protein biomarkers in neurological diseases