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PXD038547

PXD038547 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome characterization of HCMV virus microenvironment
DescriptionThe control of host processes which influence cell-cell communication is central to determining the outcome of a virus infection in tissue. Despite this, it remains unclear how cells either in close or distant proximity to an infected cell differentially respond to the primary infection. Here, we established a virus infection microenvironment to resolve molecular features and functional consequences of cell spatial address within this localized niche by mass spectrometry.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:48:04.731.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBokai Song
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Human betaherpesvirus 5; NCBI TaxID: NCBITaxon:10359;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-12-05 03:04:03ID requested
12023-05-11 11:52:42announced
22023-11-14 08:48:05announced2023-11-14: Updated project metadata.
Publication List
Song B, Sheng X, Justice JL, Lum KK, Metzger PJ, Cook KC, Kostas JC, Cristea IM, Intercellular communication within the virus microenvironment affects the susceptibility of cells to secondary viral infections. Sci Adv, 9(19):eadg3433(2023) [pubmed]
Keyword List
submitter keyword: HCMV, innate immunity, membrane contact sites, mass spectrometry,virus microenvironment, cell cycle, susceptibility
Contact List
Ileana Cristea
contact affiliationDepartment of Molecular Biology, Princeton University, NJ, US
contact emailicristea@princeton.edu
lab head
Bokai Song
contact affiliationPrinceton University
contact emailbokais@princeton.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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