PXD038456
PXD038456 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Structure of an endogenous mycobacterial MCE lipid transporter |
| Description | Mycobacterium tuberculosis, the causative agent of tuberculosis, is one of the leading causes of death due to infectious disease. The Mammalian Cell Entry proteins are essential virulence factors during infection and are thought to facilitate the import of nutrients across the highly complex mycobacterial cell envelope. We purified an endogenous Mammalian Cell Entry complex from the model mycobacterium, Mycobacterium smegmatis, identified components of the Mce1 protein complex using mass spectrometry, and determined its structure using single-particle cryo-electron microscopy and AlphaFold2. This entry contains the mass spectrometry raw files and search results for the LC-MS analysis of the purified complex. |
| HostingRepository | MassIVE |
| AnnounceDate | 2023-05-31 |
| AnnouncementXML | Submission_2023-05-31_15:11:25.598.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Beatrix Ueberheide |
| SpeciesList | scientific name: Mycobacterium smegmatis str. MC2 155; NCBI TaxID: 246196; |
| ModificationList | Oxidation; Deamidated |
| Instrument | Orbitrap Eclipse |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2022-11-29 13:12:57 | ID requested | |
| ⏵ 1 | 2023-05-31 15:11:25 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Mycobacterium smegmatis, Mammalian Cell Entry complex |
Contact List
| Beatrix Ueberheide | |
|---|---|
| contact affiliation | New York University Grossman School of Medicine |
| contact email | beatrix.ueberheide@nyulangone.org |
| lab head | |
| Beatrix Ueberheide | |
| contact affiliation | NYU School of Medicine |
| contact email | beatrixueberheide@gmail.com |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000090807/ |
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