PXD038397 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Shotgun analysis of proteins in NDUFA11 KO and WT HEK 293T cells. |
Description | The effect of the depletion of an ETC complex I protein component - NDUFA11 on the proteome in HEK 293T cells was studied. TMT-based relative quantification of protein levels were performed in NDUFA11 KO vs WT cells and in NDUFA11 KO vs WT cells that expressed an EGFP-MAPT (Tau protein) construct. In this dataset relative levels of proteins in total cell extracts and in the soluble fraction (post centrifugation at 125,000 g, at which speed protein aggregates were isolated as pellets) were measured. This dataset is directly related to the dataset PXD031374 (protein aggregates isolated as pellets post centrifugation at 125,000 g). |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:51:55.085.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Remigiusz Serwa |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF-X |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-11-26 04:06:17 | ID requested | |
1 | 2023-07-03 13:34:07 | announced | |
2 | 2023-11-14 07:01:27 | announced | 2023-11-14: Updated project metadata. |
⏵ 3 | 2024-10-22 05:51:55 | announced | 2024-10-22: Updated project metadata. |
Publication List
Keyword List
submitter keyword: NDUFA11 KO, EGFP-MAPT expression, ETC Complex I, HEK 293T |
Contact List
Prof. Agnieszka Chacinska |
contact affiliation | ReMedy International Research Agenda Unit, IMol Polish Academy of Sciences, Warsaw, Poland |
contact email | a.chacinska@imol.institute |
lab head | |
Remigiusz Serwa |
contact affiliation | The International Institute of Molecular Mechanisms and Machines, Polish Academy of Sciences |
contact email | r.serwa@imol.edu.pl |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD038397 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD038397
- Label: PRIDE project
- Name: Shotgun analysis of proteins in NDUFA11 KO and WT HEK 293T cells.