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PXD038271

PXD038271 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe immunopeptidome and proteome of DIPG
DescriptionDIPG is a devastating paediatric and young adult brainstem tumour with no cure and a median overall survival of 9 months. Cellular immunotherapy approaches require specific targeting of unique and tumour specific cell surface antigens, however, there is a paucity of known targets for DIPG. Here we used a proteomics platform approach to interrogate an array of patient derived DIPG cell lines to facilitate a multi-omics based approach to identify cell surface protein candidates enriched or unique to DIPG.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:03:56.818.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD038271
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterKirti Pandey
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; deamidated residue
InstrumentQ Exactive; Orbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-11-22 02:58:24ID requested
12023-09-25 04:22:36announced
22023-11-14 09:05:32announced2023-11-14: Updated project metadata.
32024-10-22 06:03:57announced2024-10-22: Updated project metadata.
Publication List
10.6019/PXD038271;
Pandey K, Wang SS, Mifsud NA, Faridi P, Davenport AJ, Webb AI, Sandow JJ, Ayala R, Monje M, Cross RS, Ramarathinam SH, Jenkins MR, Purcell AW, A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma. Front Oncol, 13():1192448(2023) [pubmed]
10.3389/fonc.2023.1192448;
Keyword List
submitter keyword: HLA, proteomics,DIPG, Immunopeptidomics
Contact List
Anthony Wayne Purcell
contact affiliationDepartment of Biochemistry and Molecular Biology and Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton 3800, VIC, Australia
contact emailanthony.purcell@monash.edu
lab head
Kirti Pandey
contact affiliationMonash University
contact emailkirti.pandey@monash.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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