PXD038271

PXD038271 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The immunopeptidome and proteome of DIPG
Description	DIPG is a devastating paediatric and young adult brainstem tumour with no cure and a median overall survival of 9 months. Cellular immunotherapy approaches require specific targeting of unique and tumour specific cell surface antigens, however, there is a paucity of known targets for DIPG. Here we used a proteomics platform approach to interrogate an array of patient derived DIPG cell lines to facilitate a multi-omics based approach to identify cell surface protein candidates enriched or unique to DIPG.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:03:56.818.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD038271
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Kirti Pandey
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; deamidated residue
Instrument	Q Exactive; Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-22 02:58:24	ID requested
1	2023-09-25 04:22:36	announced
2	2023-11-14 09:05:32	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 06:03:57	announced	2024-10-22: Updated project metadata.

Publication List

10.6019/PXD038271;
Pandey K, Wang SS, Mifsud NA, Faridi P, Davenport AJ, Webb AI, Sandow JJ, Ayala R, Monje M, Cross RS, Ramarathinam SH, Jenkins MR, Purcell AW, A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma. Front Oncol, 13():1192448(2023) [pubmed]
10.3389/fonc.2023.1192448;

10.6019/PXD038271;

Pandey K, Wang SS, Mifsud NA, Faridi P, Davenport AJ, Webb AI, Sandow JJ, Ayala R, Monje M, Cross RS, Ramarathinam SH, Jenkins MR, Purcell AW, A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma. Front Oncol, 13():1192448(2023) [pubmed]

10.3389/fonc.2023.1192448;

Keyword List

submitter keyword: HLA, proteomics,DIPG, Immunopeptidomics

submitter keyword: HLA, proteomics,DIPG, Immunopeptidomics

Contact List

Anthony Wayne Purcell
contact affiliation	Department of Biochemistry and Molecular Biology and Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton 3800, VIC, Australia
contact email	anthony.purcell@monash.edu
lab head
Kirti Pandey
contact affiliation	Monash University
contact email	kirti.pandey@monash.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/09/PXD038271
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/09/PXD038271

PRIDE project URI

Repository Record List

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