PXD038271 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The immunopeptidome and proteome of DIPG |
Description | DIPG is a devastating paediatric and young adult brainstem tumour with no cure and a median overall survival of 9 months. Cellular immunotherapy approaches require specific targeting of unique and tumour specific cell surface antigens, however, there is a paucity of known targets for DIPG. Here we used a proteomics platform approach to interrogate an array of patient derived DIPG cell lines to facilitate a multi-omics based approach to identify cell surface protein candidates enriched or unique to DIPG. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:03:56.818.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD038271 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Kirti Pandey |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; deamidated residue |
Instrument | Q Exactive; Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-11-22 02:58:24 | ID requested | |
1 | 2023-09-25 04:22:36 | announced | |
2 | 2023-11-14 09:05:32 | announced | 2023-11-14: Updated project metadata. |
⏵ 3 | 2024-10-22 06:03:57 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.6019/PXD038271; |
Pandey K, Wang SS, Mifsud NA, Faridi P, Davenport AJ, Webb AI, Sandow JJ, Ayala R, Monje M, Cross RS, Ramarathinam SH, Jenkins MR, Purcell AW, A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma. Front Oncol, 13():1192448(2023) [pubmed] |
10.3389/fonc.2023.1192448; |
Keyword List
submitter keyword: HLA, proteomics,DIPG, Immunopeptidomics |
Contact List
Anthony Wayne Purcell |
contact affiliation | Department of Biochemistry and Molecular Biology and Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton 3800, VIC, Australia |
contact email | anthony.purcell@monash.edu |
lab head | |
Kirti Pandey |
contact affiliation | Monash University |
contact email | kirti.pandey@monash.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/09/PXD038271 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD038271
- Label: PRIDE project
- Name: The immunopeptidome and proteome of DIPG