PXD038237

PXD038237 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The NFIB/CARM1 Partnership is a Therapeutic Target for Small Cell Lung Cancer
Description	This project identified NFI family members as CARM1 substrates. NFIB was previously reported to play a critical role in the development of small cell lung cancer. We provided evidence that the arginine methylation of NFIB is required for its oncogenic function in small cell lung cancer.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:29:17.935.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD038237
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Maria Person
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-21 16:13:11	ID requested
1	2023-02-07 14:20:18	announced
⏵ 2	2023-11-14 08:29:20	announced	2023-11-14: Updated project metadata.

Publication List

10.6019/PXD038237;
Gao G, Hausmann S, Flores NM, Benitez AM, Shen J, Yang X, Person MD, Gayatri S, Cheng D, Lu Y, Liu B, Mazur PK, Bedford MT, The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer. Nat Commun, 14(1):363(2023) [pubmed]

10.6019/PXD038237;

Gao G, Hausmann S, Flores NM, Benitez AM, Shen J, Yang X, Person MD, Gayatri S, Cheng D, Lu Y, Liu B, Mazur PK, Bedford MT, The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer. Nat Commun, 14(1):363(2023) [pubmed]

Keyword List

submitter keyword: arginine methylation,CARM1, NFIB, TRIM29, SCLC

submitter keyword: arginine methylation,CARM1, NFIB, TRIM29, SCLC

Contact List

Mark T. Bedford
contact affiliation	Professor, Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX
contact email	mtbedford@mdanderson.org
lab head
Maria Person
contact affiliation	University of Texas at Austin
contact email	mperson@austin.utexas.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD038237
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD038237

PRIDE project URI

Repository Record List

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