PXD038170

PXD038170 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of the effects of DDX20 deletion in spermatogonia
Description	To investigate the role of DDX20 in spermatogenesis, we generated Ddx20 flox/flox Ddx4-Cre mice to make a germ cell-specific Ddx20 knockout, and isolated spermatogonia from four-day-old mouse testes by THY1 magnetic beads. We then performed proteomic analysis using protein lysates obtained from THY1 + spermatogonia.
HostingRepository	iProX
AnnounceDate	2024-04-24
AnnouncementXML	Submission_2024-04-28_23:35:58.517.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dingfeng Zou
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-15 22:14:40	ID requested
1	2024-04-24 01:17:30	announced
⏵ 2	2024-04-28 23:35:59	announced	2024-04-29: Update information.

Zou D, Li K, Su L, Liu J, Lu Y, Huang R, Li M, Mang X, Geng Q, Li P, Tang J, Yu Z, Zhang Z, Chen D, Miao S, Yu J, Yan W, Song W, DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice. Dev Cell, ():(2024) [pubmed]

submitter keyword: DDX20, proteomics, spermatogonia, knockout

Wei Song
contact affiliation	Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College
contact email	roy_sw0925@sina.com
lab head
Dingfeng Zou
contact affiliation	Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College
contact email	dfmufu@163.com
dataset submitter

iProX dataset URI