PXD038167

PXD038167 is an original dataset announced via ProteomeXchange.

Title	Identification of ADAR1 associated proteins
Description	To understand how ADAR1 controls genome stability, affinity purification and mass spectrometry were employed to identify the interactomes of ADAR1 with cellular extracts from HeLa cells stably expressing FLAG-ADAR1.Mass spectrometry analysis of FLAG-ADAR1 associated proteins. The differential protein bands of the immunoprecipitates from cellular extracts of HeLa cells were retrieved from silver stained SDS-PAGE, digested with trypsin and analyzed by mass spectrometry.
HostingRepository	iProX
AnnounceDate	2022-11-15
AnnouncementXML	Submission_2023-12-04_21:11:42.111.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kaiwen Bao
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-15 20:49:01	ID requested
1	2022-11-15 20:49:28	announced
⏵ 2	2023-12-04 21:11:43	announced	2023-12-05: Update publication information.

Zhang B, Li Y, Zhang J, Wang Y, Liang C, Lu T, Zhang C, Liu L, Qin Y, He J, Zhao X, Yu J, Hao J, Yang J, Li MJ, Yao Z, Ma S, Cheng H, Cheng T, Shi L, ADAR1 links R-loop homeostasis to ATR activation in replication stress response. Nucleic Acids Res, 51(21):11668-11687(2023) [pubmed]

submitter keyword: ADAR1, Immunopurification, Genome stability

Lei Shi
contact affiliation	Tianjin medical university
contact email	shilei@tmu.edu.cn
lab head
Kaiwen Bao
contact affiliation	Tianjin medical university
contact email	baokaiwen@tmu.edu.cn
dataset submitter

iProX dataset URI