PXD038147

PXD038147 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteome Analysis of stromal cells embedded in nanocomposite hydrogels stimulated with ultrasound
Description	The regeneration of cartilage is a crucial aspect in the treatment of osteoarthritis. In recent years, cartilage regeneration has been pursued through several bioengineering strategies and using different stem cell types, such as adipose tissue-derived mesenchymal stromal cells (ASCs), however with a rather inefficient expression of key chondrogenic markers. Here, we analyzed the proteome of ASCs embedded in a nanocomposite hydrogel stimulated with ultrasound waves, focusing on pathways related to cartilage regeneration.
HostingRepository	PRIDE
AnnounceDate	2024-05-24
AnnouncementXML	Submission_2024-05-24_00:55:59.453.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD038147
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Manuela Piazzi
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-15 04:01:45	ID requested
⏵ 1	2024-05-24 00:56:01	announced

Publication List

10.1021/acsnano.3c08738;
Ricotti L, Cafarelli A, Manferdini C, Trucco D, Vannozzi L, Gabusi E, Fontana F, Dolzani P, Saleh Y, Lenzi E, Columbaro M, Piazzi M, Bertacchini J, Aliperta A, Cain M, Gemmi M, Parlanti P, Jost C, Fedutik Y, Nessim GD, Telkhozhayeva M, Teblum E, Dumont E, Delbaldo C, Codispoti G, Martini L, Tschon M, Fini M, Lisignoli G, , in Both a Normal and Inflammatory Milieu. ACS Nano, 18(3):2047-2065(2024) [pubmed]
10.6019/PXD038147;

10.1021/acsnano.3c08738;

Ricotti L, Cafarelli A, Manferdini C, Trucco D, Vannozzi L, Gabusi E, Fontana F, Dolzani P, Saleh Y, Lenzi E, Columbaro M, Piazzi M, Bertacchini J, Aliperta A, Cain M, Gemmi M, Parlanti P, Jost C, Fedutik Y, Nessim GD, Telkhozhayeva M, Teblum E, Dumont E, Delbaldo C, Codispoti G, Martini L, Tschon M, Fini M, Lisignoli G, , in Both a Normal and Inflammatory Milieu. ACS Nano, 18(3):2047-2065(2024) [pubmed]

10.6019/PXD038147;

Keyword List

submitter keyword: Human, nanocomposite hydrogel, LC-MSMS, Adipose tissue-derived mesenchymal stromal cells, Osteoarthritis, LIPUS

submitter keyword: Human, nanocomposite hydrogel, LC-MSMS, Adipose tissue-derived mesenchymal stromal cells, Osteoarthritis, LIPUS

Contact List

Dr Gina Lisignoli
contact affiliation	Rizzoli Orthopedic Institute IRCCS Laboratory of Immunorheumatology and Tissue Regeneration Bologna, Italy
contact email	gina.lisignoli@ior.it
lab head
Manuela Piazzi
contact affiliation	Institute of Molecular Genetics - National Research Council of Italy
contact email	manuela.piazzi@cnr.it
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD038147
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD038147

PRIDE project URI

Repository Record List

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