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PXD038091

PXD038091 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComparative proteomic profiles of Schistosoma japonicum male worms derived from single-sex and bisexual infections
DescriptionSchistosomiasis, which is caused by parasitic schistosomes, remains the second most prevalent parasitic disease of mammals worldwide. To successfully maintain fecundity, schistosomes have evolved a lifecycle that involves the cooperation of morphologically distinct male and female forms. Eggs produced by worm pairs are vital to the lifecycle of the parasite and are responsible for pathogenesis. Understanding the reproductive mechanism of schistosomes will help to control infection. In this study, the proteomic profiles of single-sex infected male (SM) worms and bisexual infected mated male (MM) worms of Schistosoma japonicum at 18, 21, 23, and 25 days p.i. were identified through data-independent acquisition. In total, 674 differentially expressed proteins (DEPs) were identified for the SM and MM worms at all four timepoints. Bioinformatic analysis demonstrated that most of the DEPs were involved in biosynthetic processes including locomotion, cell growth and death, cell motility, and metabolic processes such as protein metabolism and glucose metabolism.
HostingRepositoryiProX
AnnounceDate2022-11-11
AnnouncementXMLSubmission_2023-12-06_19:05:19.012.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYamei Jin
SpeciesList scientific name: Schistosoma japonicum; NCBI TaxID: 6182;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-11-10 21:00:10ID requested
12022-11-10 21:01:15announced
22023-12-06 19:05:21announced2023-12-07: Update information.
Publication List
Zhong H, Wu L, Ren Y, Qin F, Jin Y, Comparative proteomic profiles of Schistosoma japonicum male worms derived from single-sex and bisexual infections. Int J Parasitol, 52(13-14):815-828(2022) [pubmed]
Keyword List
submitter keyword: Schistosoma japonicum,Male worms, Proteomics, Differentially expressed proteins
Contact List
Yamei Jin
contact affiliationShanghai veterinary research institute
contact emailyameijin@shvri.ac.cn
lab head
Yamei Jin
contact affiliationShanghai veterinary research institute
contact emailyameijin@shvri.ac.cn
dataset submitter
Full Dataset Link List
iProX dataset URI