PXD038091
PXD038091 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Comparative proteomic profiles of Schistosoma japonicum male worms derived from single-sex and bisexual infections |
Description | Schistosomiasis, which is caused by parasitic schistosomes, remains the second most prevalent parasitic disease of mammals worldwide. To successfully maintain fecundity, schistosomes have evolved a lifecycle that involves the cooperation of morphologically distinct male and female forms. Eggs produced by worm pairs are vital to the lifecycle of the parasite and are responsible for pathogenesis. Understanding the reproductive mechanism of schistosomes will help to control infection. In this study, the proteomic profiles of single-sex infected male (SM) worms and bisexual infected mated male (MM) worms of Schistosoma japonicum at 18, 21, 23, and 25 days p.i. were identified through data-independent acquisition. In total, 674 differentially expressed proteins (DEPs) were identified for the SM and MM worms at all four timepoints. Bioinformatic analysis demonstrated that most of the DEPs were involved in biosynthetic processes including locomotion, cell growth and death, cell motility, and metabolic processes such as protein metabolism and glucose metabolism. |
HostingRepository | iProX |
AnnounceDate | 2022-11-11 |
AnnouncementXML | Submission_2023-12-06_19:05:19.012.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yamei Jin |
SpeciesList | scientific name: Schistosoma japonicum; NCBI TaxID: 6182; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-11-10 21:00:10 | ID requested | |
1 | 2022-11-10 21:01:15 | announced | |
⏵ 2 | 2023-12-06 19:05:21 | announced | 2023-12-07: Update information. |
Publication List
Zhong H, Wu L, Ren Y, Qin F, Jin Y, Comparative proteomic profiles of Schistosoma japonicum male worms derived from single-sex and bisexual infections. Int J Parasitol, 52(13-14):815-828(2022) [pubmed] |
Keyword List
submitter keyword: Schistosoma japonicum,Male worms, Proteomics, Differentially expressed proteins |
Contact List
Yamei Jin | |
---|---|
contact affiliation | Shanghai veterinary research institute |
contact email | yameijin@shvri.ac.cn |
lab head | |
Yamei Jin | |
contact affiliation | Shanghai veterinary research institute |
contact email | yameijin@shvri.ac.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |