PXD038088
PXD038088 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | TMEM135 Links Peroxisomes to the Regulation of Brown Fat Mitochondrial Fission and Energy Homeostasis |
| Description | To understand the mechanism through which peroxisomes regulate mitochondrial dynamics, we characterized changes in the mitochondrial proteome resulting from peroxisome deficiency. To this end, we isolated mitochondria from BAT of cold-treated Pex16-AKO and control mice and performed mass spectrometry-based proteomics. |
| HostingRepository | MassIVE |
| AnnounceDate | 2023-09-29 |
| AnnouncementXML | Submission_2023-09-29_12:53:30.773.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Donghua Hu |
| SpeciesList | scientific name: Mus |
| ModificationList | unknown modification |
| Instrument | instrument model |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2022-11-10 14:03:07 | ID requested | |
| ⏵ 1 | 2023-09-29 12:53:31 | announced |
Publication List
| Donghua Hu, Min Tan, Dongliang Lu, Brian Kleiboeker, Xuejing Liu, Hongsuk Park, Alexxai V. Kravitz, Kooresh I. Shoghi, Yu-Hua Tseng, Babak Razani, Akihiro Ikeda, and Irfan J. Lodhi. TMEM135 Links Peroxisomes to the Regulation of Brown Fat Mitochondrial Fission and Energy Homeostasis. Hu, D., Tan, M., Lu, D. et al. TMEM135 links peroxisomes to the regulation of brown fat mitochondrial fission and energy homeostasis. Nat Commun 14, 6099 (2023). |
Keyword List
| submitter keyword: Brown adipose tissue, Transmembrane protein 135, Mitochondrial dynamics, Energy Homeostasis |
Contact List
| Irfan J. Lodhi | |
|---|---|
| contact affiliation | Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine |
| contact email | ilodhi@wustl.edu |
| lab head | |
| Donghua Hu | |
| contact affiliation | Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine |
| contact email | hudonghua@wustl.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000090693/ |
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