PXD038055

PXD038055 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	TMT-16plex analysis of 25 individual human liver microsome and cytosol
Description	Comprehensive proteomic analysis for human liver microsome and human liver cytosol from 25 individual donors focusing on drug metabolising enzymes with relative quantification with TMTpro.
HostingRepository	jPOST
AnnounceDate	2023-11-09
AnnouncementXML	Submission_2023-11-26_22:30:20.753.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	takashi kudo
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	L-methionine sulfoxide; TMT6plex reporter+balance reagent acylated N-terminal; S-carboxamidomethyl-L-cysteine; TMT6plex reporter+balance reagent N-acylated residue; O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine; alpha-amino acetylated residue; Met-loss; deamidated L-glutamine; deamidated L-asparagine
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-08 18:19:07	ID requested
1	2023-11-08 07:00:06	announced
⏵ 2	2023-11-26 22:30:21	announced	2023-11-27: Updated PubMed.

Publication List

Kudo T, Hashiba S, Fukami T, Morinaga G, Nishiyama K, Ichida H, Hirosawa K, Matsui A, Ishiguro N, Nakajima M, Development and Validation of a Proteomic Correlation Profiling Technique to Detect and Identify Enzymes Involved in Metabolism of Drugs of Concern. Drug Metab Dispos, 51(7):824-832(2023) [pubmed]

Kudo T, Hashiba S, Fukami T, Morinaga G, Nishiyama K, Ichida H, Hirosawa K, Matsui A, Ishiguro N, Nakajima M, Development and Validation of a Proteomic Correlation Profiling Technique to Detect and Identify Enzymes Involved in Metabolism of Drugs of Concern. Drug Metab Dispos, 51(7):824-832(2023) [pubmed]

Keyword List

submitter keyword: human liver microsome, human liver cytosol, drug metabolizing enzymes

submitter keyword: human liver microsome, human liver cytosol, drug metabolizing enzymes

Contact List

Takuma Katayama
lab head
takashi kudo
contact affiliation	Nippon Boehringer Ingelheim, Co., Ltd.
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001523/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001523/