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PXD038013

PXD038013 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative proteome analysis to map the targets of small molecule UM171
DescriptionEarlier we identified the protein degradation properties of small molecule UM171 (Subramaniam et al., 2020, Blood). Here we employed quantitative proteomics approach to map the global targets of UM171. Our study revealed multiple targets including the members of CoREST complex such as RCOR1 and LSD1.
HostingRepositoryPRIDE
AnnounceDate2023-03-26
AnnouncementXMLSubmission_2023-03-26_08:31:19.073.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterEricFischer
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumenttimsTOF Pro 2
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-11-07 09:57:33ID requested
12023-03-26 08:31:19announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: UM171, Protein degradation., CoREST
Contact List
EricFischer
contact affiliationDepartment of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
contact emailEric_fischer@dfci.harvard.edu
lab head
EricFischer
contact affiliationDana-Farber Cancer Institute
contact emaileric_fischer@dfci.harvard.edu
dataset submitter
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Dataset FTP location
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