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PXD038012

PXD038012 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTestis-specific serine kinase 3 is required for sperm morphogenesis and male fertility
DescriptionTSSK3 is expressed in elongating sperm and localizes to the sperm tail. To define the essential roles of TSSK3 in vivo and elucidate the mechanisms causing the phenotype, we conducted phosphoproteomics using purified germ cells from Tssk3 HET and KO testes.
HostingRepositoryPRIDE
AnnounceDate2023-11-21
AnnouncementXMLSubmission_2023-11-21_15:59:58.131.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAntrix Jain
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListphosphorylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-11-07 09:57:16ID requested
12023-11-21 16:00:00announced
Publication List
Nozawa K, Garcia TX, Kent K, Leng M, Jain A, Malovannaya A, Yuan F, Yu Z, Ikawa M, Matzuk MM, Testis-specific serine kinase 3 is required for sperm morphogenesis and male fertility. Andrology, 11(5):826-839(2023) [pubmed]
10.1111/andr.13314;
Keyword List
submitter keyword: proteomics, oligoteratozoospermia,Knockout mouse, teratozoospermia, oligozoospermia
Contact List
Martin M. Matzuk
contact affiliationCenter for Drug Discovery, Baylor College of Medicine, Houston, TX Department of Pathology & Immunology, BCM, Houston, TX
contact emailmmatzuk@bcm.edu
lab head
Antrix Jain
contact affiliationBaylor College of Medicine
contact emailantrixj@bcm.edu
dataset submitter
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Dataset FTP location
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