PXD037999

PXD037999 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteome analysis to map the targets of small molecule UM171
Description	Earlier we identified the protein degradation properties of small molecule UM171 (Subramaniam et al., 2020, Blood). Here we employed quantitative proteomics approach to map the global targets of UM171. Our study revealed multiple targets including the members of CoREST complex such as RCOR1 and LSD1.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:59:21.639.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sudip Ghosh
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-07 09:42:53	ID requested
⏵ 1	2023-11-14 08:59:22	announced

Dataset with its publication pending

submitter keyword: UM171, Protein degradation., CoREST

Jenny Hansson
contact affiliation	Proteomic Hematology Division of Molecular Hematology Lund Stem Cell Center, Lund University
contact email	jenny.hansson@med.lu.se
lab head
Sudip Ghosh
contact affiliation	Proteomic Hematology, Department of Experimental Medical Science, Lund Stem Cell Center, Lund University
contact email	sudip.ghosh@med.lu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD037999

PRIDE project URI

• PRIDE
  1. PXD037999
     1. Label: PRIDE project
     2. Name: Quantitative proteome analysis to map the targets of small molecule UM171