PXD037994

PXD037994 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification of post-translational modifications on soluble alpha-Synuclein purified from various alpha-Synucleinopathies by LC-MSMS
Description	LC-MS/MS analyses were performed on soluble alpha-Syn purified from PD and various alpha-Synucleinopathies to systematically explore the landscape of post-translational modifications (PTMs) on soluble alpha-Syn, leading to the identification of a large number of novel alpha-Syn PTMs.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:24:35.245.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chao Peng
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monomethylated residue; phosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetic acid derivatized residue
Instrument	Q Exactive HF; LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-07 09:27:40	ID requested
1	2023-02-02 01:55:36	announced
⏵ 2	2023-11-14 07:24:38	announced	2023-11-14: Updated project metadata.

Publication List

Zhang S, Zhu R, Pan B, Xu H, Olufemi MF, Gathagan RJ, Li Y, Zhang L, Zhang J, Xiang W, Kagan EM, Cao X, Yuan C, Kim SJ, Williams CK, Magaki S, Vinters HV, Lashuel HA, Garcia BA, James Petersson E, Trojanowski JQ, Lee VM, Peng C, -synuclein. Nat Neurosci, 26(2):213-225(2023) [pubmed]

Zhang S, Zhu R, Pan B, Xu H, Olufemi MF, Gathagan RJ, Li Y, Zhang L, Zhang J, Xiang W, Kagan EM, Cao X, Yuan C, Kim SJ, Williams CK, Magaki S, Vinters HV, Lashuel HA, Garcia BA, James Petersson E, Trojanowski JQ, Lee VM, Peng C, -synuclein. Nat Neurosci, 26(2):213-225(2023) [pubmed]

Keyword List

submitter keyword: Human, post-translational modification, Brain, soluble a-Synuclein, alpha-Synucleinopathies

submitter keyword: Human, post-translational modification, Brain, soluble a-Synuclein, alpha-Synucleinopathies

Contact List

Chao Peng
contact affiliation	Department of Neurology, UCLA
contact email	cpeng@mednet.ucla.edu
lab head
Chao Peng
contact affiliation	UCLA
contact email	pengchao0160@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD037994
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD037994

PRIDE project URI

Repository Record List

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