PXD037951

PXD037951 is an original dataset announced via ProteomeXchange.

Title	Identifying the patients with rapid progression from hormone-sensitive to castration-resistant prostate cancer
Description	We collected 78 biopsies and analyzed the proteomic expression by pressure cycling technology and Pulsed data-independent acquisition (PCT-PulseDIA) pipeline. Next, we explore the differentially expressed proteins (DEPs) in the discovery set (n=16) which contains short (S, n=8)- and long (L, n=8)- term progression. The progression-related proteins were further identified in another dataset, modeling set (n=62), utilizing the ANOVA estimation and random forest model. Multivariable Cox regression analysis was then conducted to determine clinical and protein variables significantly associated with the progression of HSPC in the whole sample set (n=78).
HostingRepository	iProX
AnnounceDate	2022-11-04
AnnouncementXML	Submission_2023-10-25_20:53:42.739.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yaoting Sun
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-03 21:22:59	ID requested
⏵ 1	2023-10-25 20:53:43	announced

Pan C, He Y, Wang H, Yu Y, Li L, Huang L, Lyu M, Ge W, Yang B, Sun Y, Guo T, Liu Z, Identifying Patients With Rapid Progression From Hormone-Sensitive to Castration-Resistant Prostate Cancer: A Retrospective Study. Mol Cell Proteomics, 22(9):100613(2023) [pubmed]

submitter keyword: hormone-sensitive prostate cancer, castration-resistant prostate cancer

Tiannan Guo
contact affiliation	Westlake University
contact email	guotiannan@westlake.edu.cn
lab head
Yaoting Sun
contact affiliation	Westlake University
contact email	sunyaoting@westlake.edu.cn
dataset submitter

iProX dataset URI