PXD037951
PXD037951 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identifying the patients with rapid progression from hormone-sensitive to castration-resistant prostate cancer |
Description | We collected 78 biopsies and analyzed the proteomic expression by pressure cycling technology and Pulsed data-independent acquisition (PCT-PulseDIA) pipeline. Next, we explore the differentially expressed proteins (DEPs) in the discovery set (n=16) which contains short (S, n=8)- and long (L, n=8)- term progression. The progression-related proteins were further identified in another dataset, modeling set (n=62), utilizing the ANOVA estimation and random forest model. Multivariable Cox regression analysis was then conducted to determine clinical and protein variables significantly associated with the progression of HSPC in the whole sample set (n=78). |
HostingRepository | iProX |
AnnounceDate | 2022-11-04 |
AnnouncementXML | Submission_2023-10-25_20:53:42.739.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yaoting Sun |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-11-03 21:22:59 | ID requested | |
⏵ 1 | 2023-10-25 20:53:43 | announced |
Publication List
Pan C, He Y, Wang H, Yu Y, Li L, Huang L, Lyu M, Ge W, Yang B, Sun Y, Guo T, Liu Z, Identifying Patients With Rapid Progression From Hormone-Sensitive to Castration-Resistant Prostate Cancer: A Retrospective Study. Mol Cell Proteomics, 22(9):100613(2023) [pubmed] |
Keyword List
submitter keyword: hormone-sensitive prostate cancer, castration-resistant prostate cancer |
Contact List
Tiannan Guo | |
---|---|
contact affiliation | Westlake University |
contact email | guotiannan@westlake.edu.cn |
lab head | |
Yaoting Sun | |
contact affiliation | Westlake University |
contact email | sunyaoting@westlake.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |