PXD037942

PXD037942 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Thermal proteome profiling in Cryptosporidium parvum
Description	Cryptosporidium lacks tools that can identify the targets of emerging compounds that have been developed against this parasite. Thermal proteomic profiling is an unbiased approach that fulfils this unmet need by detecting changes in the thermal stability of target proteins upon the binding of their inhibitor. This technique has been successfully used in other protozoan parasites and here we report the validation and first use of thermal proteome profiling in Cryptosporidium.
HostingRepository	PRIDE
AnnounceDate	2023-06-13
AnnouncementXML	Submission_2023-06-13_10:01:51.695.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	VictorianoCorpas-Lopez
SpeciesList	scientific name: Cryptosporidium parvum Iowa II; NCBI TaxID: 353152;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-03 05:17:08	ID requested
⏵ 1	2023-06-13 10:01:52	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: drug target, lysyl-tRNA synthetase, Cryptosporodium parvum,thermal proteome profiling

submitter keyword: drug target, lysyl-tRNA synthetase, Cryptosporodium parvum,thermal proteome profiling

Contact List

MattiePawlowic
contact affiliation	WCAIR, School of Life Sciences, University of Dundee, UK
contact email	mcpawlowic@dundee.ac.uk
lab head
VictorianoCorpas-Lopez
contact affiliation	University of Dundee
contact email	vcorpaslopez@dundee.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD037942
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD037942

PRIDE project URI

Repository Record List

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