PXD037902

PXD037902 is an original dataset announced via ProteomeXchange.

Title	The brain protein secreted amyloid precursor protein alpha (sAPPalpha) regulates neurologically-important proteins of the cellular proteome and secretome of mouse primary astrocytes
Description	Mouse primary astrocytes in culture were exposed to 1 nM secreted amyloid precursor protein alpha (sAPPalpha) or PBS (control) for 2 h or 6 h and changes in the cellular proteome or secretome respectively were quantified by SWATH-MS.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:47:53.844.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Torsten Kleffmann
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-03 04:15:09	ID requested
1	2023-05-10 16:18:33	announced
⏵ 2	2023-11-14 08:47:57	announced	2023-11-14: Updated project metadata.

Peppercorn K, Kleffmann T, Hughes SM, Tate WP, ) Regulates the Cellular Proteome and Secretome of Mouse Primary Astrocytes. Int J Mol Sci, 24(8):(2023) [pubmed]

submitter keyword: Astrocytes, Amyloid Precuror Protein, proteome, secretome

Warren Perry Tate
contact affiliation	Department of Biochemistry, University of Otago, Dunedin, New Zealand
contact email	warren.tate@otago.ac.nz
lab head
Torsten Kleffmann
contact affiliation	Department of Biochemistry, University of Otago
contact email	torsten.kleffmann@otago.ac.nz
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD037902

PRIDE project URI

• PRIDE
  1. PXD037902
     1. Label: PRIDE project
     2. Name: The brain protein secreted amyloid precursor protein alpha (sAPPalpha) regulates neurologically-important proteins of the cellular proteome and secretome of mouse primary astrocytes