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PXD037902

PXD037902 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe brain protein secreted amyloid precursor protein alpha (sAPPalpha) regulates neurologically-important proteins of the cellular proteome and secretome of mouse primary astrocytes
DescriptionMouse primary astrocytes in culture were exposed to 1 nM secreted amyloid precursor protein alpha (sAPPalpha) or PBS (control) for 2 h or 6 h and changes in the cellular proteome or secretome respectively were quantified by SWATH-MS.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:47:53.844.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterTorsten Kleffmann
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListiodoacetamide derivatized residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-11-03 04:15:09ID requested
12023-05-10 16:18:33announced
22023-11-14 08:47:57announced2023-11-14: Updated project metadata.
Publication List
Peppercorn K, Kleffmann T, Hughes SM, Tate WP, ) Regulates the Cellular Proteome and Secretome of Mouse Primary Astrocytes. Int J Mol Sci, 24(8):(2023) [pubmed]
Keyword List
submitter keyword: Astrocytes, Amyloid Precuror Protein, proteome, secretome
Contact List
Warren Perry Tate
contact affiliationDepartment of Biochemistry, University of Otago, Dunedin, New Zealand
contact emailwarren.tate@otago.ac.nz
lab head
Torsten Kleffmann
contact affiliationDepartment of Biochemistry, University of Otago
contact emailtorsten.kleffmann@otago.ac.nz
dataset submitter
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Dataset FTP location
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Repository Record List
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