PXD037785

PXD037785 is an original dataset announced via ProteomeXchange.

Title	Talaroconvolutin-A treated bladder cancer for proteomics sequencing
Description	TalaA inhibits bladder cancer mainly through two approaches: 1) arresting cell cycle to suppress proliferation, 2) triggering ferroptosis to cause cell death. In molecular mechanism, TalaA can interact with MAPKs to repress the phosphorylation of transcription regulators. This study would open new avenues for bladder cancer treatment targeting MAPKs, inhibiting cell cycle and inducing ferroptosis.
HostingRepository	iProX
AnnounceDate	2022-10-27
AnnouncementXML	Submission_2024-02-25_22:06:12.085.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yong Xia
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	TMT6plex reporter fragment; phosphorylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-27 21:26:47	ID requested
⏵ 1	2024-02-25 22:06:12	announced

Xia Y, Xiang L, Yao M, Ai Z, Yang W, Guo J, Fan S, Liu N, Yang X, Proteomics, Transcriptomics, and Phosphoproteomics Reveal the Mechanism of Talaroconvolutin-A Suppressing Bladder Cancer via Blocking Cell Cycle and Triggering Ferroptosis. Mol Cell Proteomics, 22(12):100672(2023) [pubmed]

submitter keyword: Bladder cancer, Talaroconvolutin-A, proteomics, transcriptomics, phosphoproteomics, cell cycle, ferroptosis

Yong Xia
contact affiliation	Jining Medical University
contact email	xiayong0728@126.com
lab head
Yong Xia
contact affiliation	Jining Medical University
contact email	xiayong0728@126.com
dataset submitter

iProX dataset URI