PXD037757

PXD037757 is an original dataset announced via ProteomeXchange.

Title	Complexome profiling of mitochondrial protein complexes to study assembly and stability of complex I in a patient with a defect in the NDUFAF3 gene
Description	NDUFAF3 is a factor required for the coordinated assembly of the first complex of the oxidative phosphorylation system (OXPHOS). Here we used a complexome profiling of fibroblasts from a patient to analyze the consequence of a mutation in the NDUFAF3 gene on the molecular level.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:07:28.175.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ilka Wittig
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-27 02:37:46	ID requested
1	2023-08-21 05:06:59	announced
⏵ 2	2023-11-14 07:07:28	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: oxidative phosphorylation system, supercomplexes,LC-MSMS, complexome profiling

Amelie T. van der Ven
contact affiliation	Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
contact email	a.van-der-ven@uke.de
lab head
Ilka Wittig
contact affiliation	Functional Proteomics, Goethe University, Frankfurt am Main , Germany
contact email	wittig@med.uni-frankfurt.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/08/PXD037757

PRIDE project URI

• PRIDE
  1. PXD037757
     1. Label: PRIDE project
     2. Name: Complexome profiling of mitochondrial protein complexes to study assembly and stability of complex I in a patient with a defect in the NDUFAF3 gene