PXD037605

PXD037605 is an original dataset announced via ProteomeXchange.

Title	Proteomics analysis of zebrafish spinal cord regeneration following extracellular matrix manipulations
Description	Label-free mass spectrometry-based quantitative proteomics was applied to a larval zebrafish spinal cord injury model, which allows axon regeneration and functional recovery within two days (days post lesion; dpl) after a spinal cord transection in 3 day-old larvae (dpf). Proteomic profiling was performed of the lesion site at 1 dpl in control animals and animals with pdgfrb+ cell-specific overexpression of either zebrafish chondoradherin (chad; chad-mCherry fusion), fibromodulin a (fmoda; fmoda-mCherry fusion), lumican (lum; lum-mCherry fusion) or prolargin (prelp; prelp-mCherry fusion).
HostingRepository	PRIDE
AnnounceDate	2023-09-08
AnnouncementXML	Submission_2023-09-07_18:50:01.960.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	BarbaraSteigenberger
SpeciesList	scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: 7955;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-20 02:27:58	ID requested
⏵ 1	2023-09-07 18:50:02	announced

Dataset with its publication pending

submitter keyword: Zebrafish

spinal cord

regeneration

LC-MS/MS

Small leucine-rich proteoglycans

Dr. DanielWehner
contact affiliation	Max Planck Institute for the Science of Light & Max-Planck-Zentrum für Physik und Medizin Division Biological Optomechanics Staudtstr. 2 91058 Erlangen Germany
contact email	daniel.wehner@mpl.mpg.de
lab head
BarbaraSteigenberger
contact affiliation	MPI of Biochemistry
contact email	steigenberger@biochem.mpg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/09/PXD037605

PRIDE project URI

• PRIDE
  1. PXD037605
     1. Label: PRIDE project
     2. Name: Proteomics analysis of zebrafish spinal cord regeneration following extracellular matrix manipulations