PXD037475

PXD037475 is an original dataset announced via ProteomeXchange.

Title	Proteomics of exosomes derived from cisplatin-induced dormant A549 cells
Description	Lung cancer is the leading cause of cancer-related deaths worldwide. Chemotherapy kills most cancer cells, however, the residual cells enter into dormant state. The dormant cancer cells can be reactivated under specific circumstances. Tumor-derived exosomes are the main mediators of tumorigenesis. We are aiming to elucidate the roles of exosomes from cisplatin-induced dormant lung cancer cells in the tumor recurrence and metastasis. We performed differential proteome in dormant A549 cell- and A549 cell-derived exosomes.
HostingRepository	iProX
AnnounceDate	2022-10-17
AnnouncementXML	Submission_2023-01-12_19:45:28.169.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Juanjuan Xiang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-17 01:14:28	ID requested
1	2022-10-30 23:40:23	announced
⏵ 2	2023-01-12 19:45:29	announced	2023-01-13: Update publication information.

Xu J, Feng X, Yin N, Wang L, Xie Y, Gao Y, Xiang J, Exosomes from cisplatin-induced dormant cancer cells facilitate the formation of premetastatic niche in bone marrow through activating glycolysis of BMSCs. Front Oncol, 12():922465(2022) [pubmed]

submitter keyword: exosomes, dormancy, lung cancer

Juanjuan Xiang
contact affiliation	Central South University
contact email	xiangjj@csu.edu.cn
lab head
Juanjuan Xiang
contact affiliation	Central South University
contact email	xiangjj@csu.edu.cn
dataset submitter

iProX dataset URI