PXD037468

PXD037468 is an original dataset announced via ProteomeXchange.

Title	Proteomic Analysis of Protective Effects of Dl-3-n-Butylphthalide against mpp+-Induced Toxicity via downregulating P53 pathway in N2A Cells
Description	NBP significantly relived mpp+-induced cell toxicity. In addition, the neuroprotective role of NBP was implicated with P53 signaling pathway in some extent. These findings will reinforce the understanding of the mechanism of NBP in PD and identify new therapeutic targets
HostingRepository	iProX
AnnounceDate	2022-10-17
AnnouncementXML	Submission_2023-03-01_19:06:20.632.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Guofeng Yang
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-17 01:02:18	ID requested
1	2023-01-30 18:35:51	announced
2	2023-02-27 19:03:16	announced	2023-02-28: Update publication information.
⏵ 3	2023-03-01 19:06:21	announced	2023-02-28: Update publication information. 2023-03-02: Update publication information.

Zhao Y, Zhang J, Zhang Y, Li S, Gao Y, Chang C, Liu X, Xu L, Yang G, -Induced Toxicity via downregulating P53 pathway in N2A Cells. Proteome Sci, 21(1):1(2023) [pubmed]

submitter keyword: Parkinson’s Disease, Quantitative proteomic analysis, Tandem mass tag, Dl-3-n-Butylphthalide (NBP), P53 pathway, mpp+, Neuroprotection

Guofeng Yang
contact affiliation	The second hospital of hebei medical university
contact email	gf_yang71@126.com
lab head
Guofeng Yang
contact affiliation	The second hospital of hebei medical university
contact email	gf_yang71@126.com
dataset submitter

iProX dataset URI