PXD037420
PXD037420 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomics reveals multiple effects of titanium dioxide and silver nanoparticles in the metabolism of turbot, Scophthalmus maximus |
Description | This project aimed to assess the toxicity underlying the exposure of Turbot (Scophthalmus maximus), an economically valuable fish species, to TiO2 and Ag nanoparticles (NPs). To carry out the study, juvenile fish were exposed to TiO2 and Ag NPs incorporated in the diet. After 14 days of exposure fish were euthanized and liver and kidney samples collected for proteomics. The shotgun proteomics analysis revealed quantitative changes in multiple proteins. The results suggest effects of TiO2 and Ag NPs in energy/lipid metabolism and for instance alterations in ribosome functions, protein biosynthesis and related processes. This proteomic study provided as well candidate biomarkers for NPs exposure in aquaculture species. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_07:50:36.360.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Alexandre Campos |
SpeciesList | scientific name: Scophthalmus maximus; NCBI TaxID: 52904; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF; LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-10-14 04:50:46 | ID requested | |
1 | 2022-10-18 02:36:03 | announced | |
⏵ 2 | 2023-11-14 07:50:37 | announced | 2023-11-14: Updated project metadata. |
Publication List
Ara, ú, jo MJ, Sousa ML, Fonseca E, Felpeto AB, Martins JC, V, á, zquez M, Mallo N, Rodriguez-Lorenzo L, Quarato M, Pinheiro I, Turkina MV, L, ó, pez-May, á, n JJ, Pe, ñ, a-V, á, zquez E, Barciela-Alonso MC, Spuch-Calvar M, Oliveira M, Bermejo-Barrera P, Cabaleiro S, Espi, ñ, a B, Vasconcelos V, Campos A, Proteomics reveals multiple effects of titanium dioxide and silver nanoparticles in the metabolism of turbot, Scophthalmus maximus. Chemosphere, 308(Pt 1):136110(2022) [pubmed] |
Keyword List
submitter keyword: Atlantic area Nanoculture |
Contact List
Alexandre Campos | |
---|---|
contact affiliation | CIIMAR - Interdisciplinary Centre of Marine and Environmental Research, Porto University |
contact email | acampos@ciimar.up.pt |
lab head | |
Alexandre Campos | |
contact affiliation | CIIMAR |
contact email | acampos@ciimar.up.pt |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD037420 |
PRIDE project URI |
Repository Record List
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