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PXD037420

PXD037420 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomics reveals multiple effects of titanium dioxide and silver nanoparticles in the metabolism of turbot, Scophthalmus maximus
DescriptionThis project aimed to assess the toxicity underlying the exposure of Turbot (Scophthalmus maximus), an economically valuable fish species, to TiO2 and Ag nanoparticles (NPs). To carry out the study, juvenile fish were exposed to TiO2 and Ag NPs incorporated in the diet. After 14 days of exposure fish were euthanized and liver and kidney samples collected for proteomics. The shotgun proteomics analysis revealed quantitative changes in multiple proteins. The results suggest effects of TiO2 and Ag NPs in energy/lipid metabolism and for instance alterations in ribosome functions, protein biosynthesis and related processes. This proteomic study provided as well candidate biomarkers for NPs exposure in aquaculture species.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_07:50:36.360.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAlexandre Campos
SpeciesList scientific name: Scophthalmus maximus; NCBI TaxID: 52904;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF; LTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-10-14 04:50:46ID requested
12022-10-18 02:36:03announced
22023-11-14 07:50:37announced2023-11-14: Updated project metadata.
Publication List
Ara, ú, jo MJ, Sousa ML, Fonseca E, Felpeto AB, Martins JC, V, á, zquez M, Mallo N, Rodriguez-Lorenzo L, Quarato M, Pinheiro I, Turkina MV, L, ó, pez-May, á, n JJ, Pe, ñ, a-V, á, zquez E, Barciela-Alonso MC, Spuch-Calvar M, Oliveira M, Bermejo-Barrera P, Cabaleiro S, Espi, ñ, a B, Vasconcelos V, Campos A, Proteomics reveals multiple effects of titanium dioxide and silver nanoparticles in the metabolism of turbot, Scophthalmus maximus. Chemosphere, 308(Pt 1):136110(2022) [pubmed]
Keyword List
submitter keyword: Atlantic area Nanoculture
Contact List
Alexandre Campos
contact affiliationCIIMAR - Interdisciplinary Centre of Marine and Environmental Research, Porto University
contact emailacampos@ciimar.up.pt
lab head
Alexandre Campos
contact affiliationCIIMAR
contact emailacampos@ciimar.up.pt
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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