PXD037414 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | MS-based characterization of YTHDC1 interactome |
Description | Heat shock induces a cell response leading to profound changes in genome expression. Recently, N6-methyladenosine (m6A) RNA modification has been implicated in this response, but with limited information of its role in the heat-induced reprograming of gene expression. Most of m6A molecular and cellular functions rely on m6A readers and the best characterized m6A readers are members of the YTH-domain-containing protein family present from yeast to humans. To investigate the function of the nuclear m6A reader YTHDC1, we characterized its binding partners. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:19:34.674.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yohann Couté |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-10-14 04:41:18 | ID requested | |
1 | 2023-01-11 01:05:15 | announced | |
⏵ 2 | 2023-11-14 08:19:35 | announced | 2023-11-14: Updated project metadata. |
Publication List
Timcheva K, Dufour S, Touat-Todeschini L, Burnard C, Carpentier MC, Chuffart F, Merret R, Helsmoortel M, Ferr, é S, Gr, é, zy A, Cout, é Y, Rousseaux S, Khochbin S, Vourc'h C, Bousquet-Antonelli C, Kiernan R, Seigneurin-Berny D, Verdel A, Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression. Cell Rep, 41(11):111784(2022) [pubmed] |
Keyword List
submitter keyword: Human, nuclear m6A reader, YTHDC1, nanoLC-MS/MS, interactome |
Contact List
Yohann Couté |
contact affiliation | EDyP |
contact email | yohann.coute@cea.fr |
lab head | |
Yohann Couté |
contact affiliation | EDyP |
contact email | yohann.coute@cea.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD037414
- Label: PRIDE project
- Name: MS-based characterization of YTHDC1 interactome