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PXD037365

PXD037365 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLung Adenocarcinoma (A549) Immunopeptidomics
DescriptionAlterations in cellular antigen processing and presenting machinery has gained increased interest as a hallmark of cancer-related inflammation. Growing evidence suggest that proteasome composition and immunoproteasome expression can influence antigen processing. By performing immunopeptidomics on A549 lung adenocarcinoma cell line following depletion of proteasome regulator PSME4 we identified alterations in the antigenic landscape resulting from changes in proteasome processing.
HostingRepositoryPRIDE
AnnounceDate2024-10-07
AnnouncementXMLSubmission_2024-10-07_11:10:19.055.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAaron Javitt
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmono N-acetylated residue; monohydroxylated residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-10-13 09:50:31ID requested
12024-10-07 11:10:19announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Immunopeptidomics, Proteasome, NSCLC
Contact List
Yifat Merbl
contact affiliationDept. of Systems Immunology Weizmann Institute of Science
contact emailyifat.merbl@weizmann.ac.il
lab head
Aaron Javitt
contact affiliationWeizmann Institue of Science
contact emailaaronjavitt@gmail.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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