PXD037317 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Breast cancer cell MCF7+CYP1B1-AS1 LC-MS/MS |
Description | Long non-coding Rnas (lncRNAs) can act as oncogenes or tumor suppressors to regulate cancer development. We found that CYP1B1-AS1 was down-regulated in breast cancer tissues and correlated with the prognosis of patients. Lentiviral vectors were used to overexpress CYP1B1-AS1 in MCF7 cells, and the target proteins bound to CYP1B1-AS1 were detected by pulldown assay and mass spectrometry. The function of CYP1B1-AS1 is unknown. Our study revealed the molecular mechanism of CYP1B1-AS1 inhibiting breast cancer proliferation in breast cancer, and provided a new strategy for the treatment of breast cancer targeting lncRNA. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_09:06:44.673.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | li tang |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-10-12 08:31:16 | ID requested | |
1 | 2023-10-24 10:52:21 | announced | |
⏵ 2 | 2023-11-14 09:06:52 | announced | 2023-11-14: Updated project metadata. |
Publication List
Tang L, Wei D, Xu X, Mo D, Cheng D, Yan F, FOXO1-regulated lncRNA CYP1B1-AS1 suppresses breast cancer cell proliferation by inhibiting neddylation. Breast Cancer Res Treat, 202(2):397-408(2023) [pubmed] |
Keyword List
submitter keyword: CYP1B1-AS1,MCF7 |
Contact List
Feng Yan |
contact affiliation | Department of Clinical Laboratory, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China. |
contact email | yanfeng@jszlyy.com.cn |
lab head | |
li tang |
contact affiliation | Jiangsu Cancer Hospital |
contact email | tangyinhome@126.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD037317 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD037317
- Label: PRIDE project
- Name: Breast cancer cell MCF7+CYP1B1-AS1 LC-MS/MS