PXD037272

PXD037272 is an original dataset announced via ProteomeXchange.

Title	Human Prostate Cancer epithelial-fibroblast cell signalling by CTAP-MS
Description	A greater understanding of cell signaling events that occur within the prostate cancer tumor microenvironment (TME), for example between cancer-associated fibroblasts (CAFs) and prostate epithelial or cancer cells, may identify novel biomarkers and more effective therapeutic strategies for this disease. To address this, we used cell-type specific labelling with amino acid precursors (CTAP) to define cell type-specific phosphoproteomic changes that occur when prostate epithelial cells are co-cultured with normal patient-derived prostate fibroblasts (NPFs) versus matched CAFs.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:38:06.822.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Terry Lim
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-10 08:09:06	ID requested
1	2023-03-10 23:15:14	announced
⏵ 2	2023-11-14 08:38:09	announced	2023-11-14: Updated project metadata.

Clark KC, Nguyen EV, Niranjan B, Wu Y, Lim Kam Sian TCC, Horvath LG, Taylor RA, Daly RJ, Cell-Type-Specific Signalling Networks Impacted by Prostate Epithelial-Stromal Intercellular Communication. Cancers (Basel), 15(3):(2023) [pubmed]

submitter keyword: CTAP-MS, human, CAF,prostate, fibroblast

Roger Daly
contact affiliation	Monash Biomedicine Discovery Institute Department of Biochemistry and Molecular Biology Monash University Level 1, Building 77, Clayton Campus 23 Innovation Walk Clayton VIC 3800 Australia
contact email	roger.daly@monash.edu
lab head
Terry Lim
contact affiliation	Monash University
contact email	terry.lim@monash.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD037272

PRIDE project URI

• PRIDE
  1. PXD037272
     1. Label: PRIDE project
     2. Name: Human Prostate Cancer epithelial-fibroblast cell signalling by CTAP-MS