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PXD037252

PXD037252 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of FBXL6 Knockdown cells proteome
DescriptionFBXL6 is E3 ubiquitin ligase that we suspected to be involved in mitochondrial functions. We have investigated how deletion of this E3s by CRSIPR/Cas in Hela cells affects the cellular proteome. We compared this proteome to cells treated with CRISPR Non-Targeting Control (control cells).
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_09:05:32.090.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDupuy Jean-William
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-10-10 07:43:48ID requested
12023-09-25 05:03:52announced
22023-11-14 09:05:33announced2023-11-14: Updated project metadata.
Publication List
Lavie J, Lalou C, Mahfouf W, Dupuy JW, Lacaule A, Cywinska AA, Lacombe D, Duch, ê, ne AM, Raymond AA, Rezvani HR, Ngondo RP, B, é, nard G, The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins. Cell Rep, 42(6):112579(2023) [pubmed]
Keyword List
submitter keyword: Quantitative proteome, Human cell line
Contact List
Giovanni Benard
contact affiliationLaboratoire Maladies Rares: Génétique et Métabolisme- INSERM U1211, 33000 Bordeaux, France
contact emailgiovanni.benard@inserm.fr
lab head
Dupuy Jean-William
contact affiliationPlateforme Proteome Bordeaux
contact emailjean-william.dupuy@u-bordeaux.fr
dataset submitter
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Dataset FTP location
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PRIDE project URI
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