Update publication information. Based on the gene ontology (GO) results, we found that proteins associated with responses or processes related to stimulus, immune system, signalling, cell killing, and antioxidant activity were more up-regulated after MiBaMc treatment. In contrast, proteins that related to cell integrity and cell growth were more down-regulated. Those results indicated that MiBaMc induced strengthened tumour damage, which should be attributed to the synergistic effect induced by hyperthermia and ROS. Furthermore, the prominent upregulation of proteins associated with antioxidant activity also directly indicated the enhanced oxidative pressure of tumours in the MiBaMc treated group. Specifically, there were obvious overlays between proteins associated with heat shock, oxidative stress, and cell death. Thus both photothermal-induced hyperthermia and photodynamic-induced oxidative damage contributed to immune cell death. Moreover, a significant enhancement in the protein level associated with immune response was observed from the GO analysis, suggesting the antitumour capacity should be attributed to the systemic immune activation of the MiBaMc. This phenomenon can also be verified from the prominent overlays between proteins associated with immune response, inflammation, and bacteria infection.