PXD037059

PXD037059 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The Legionella protein VpdC is a ubiquitin-activated phospholipase effector
Description	The goal of this project was to identify the host factor(s) required for allosteric activation of the phospholipase VpdC from the intracellular pathogen Legionella pneumophila. For that reason, we performed co-precipitation analyses from lysate of transiently transfected HEK293T cells producing either Red Fluorescent Protein (RFP)-tagged VpdC(257-884) or RFP-VpdC(257-610) as bait.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:47:47.874.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD037059
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	David Anderson
SpeciesList	scientific name: Legionella pneumophila; NCBI TaxID: 446; scientific name: Legionella pneumophila; NCBI TaxID: NCBITaxon:446;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-09-28 01:00:03	ID requested
1	2023-06-12 04:56:42	announced
2	2023-11-14 09:00:46	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 05:47:48	announced	2024-10-22: Updated project metadata.

Publication List

10.1073/pnas.2209149119;
Li X, Anderson DE, Chang YY, Jarnik M, Machner MP, vacuole expansion during infection. Proc Natl Acad Sci U S A, 119(48):e2209149119(2022) [pubmed]
10.6019/PXD037059;

10.1073/pnas.2209149119;

Li X, Anderson DE, Chang YY, Jarnik M, Machner MP, vacuole expansion during infection. Proc Natl Acad Sci U S A, 119(48):e2209149119(2022) [pubmed]

10.6019/PXD037059;

Keyword List

submitter keyword: Host-pathogen interaction
intracellular pathogen
Legionnaires' disease
translocated effector
host cell;

submitter keyword: Host-pathogen interaction

intracellular pathogen

Legionnaires' disease

translocated effector

host cell;

Contact List

Matthias Peter Machner
contact affiliation	Section on Microbial Pathogenesis, NICHD, NIH, Department of Health and Human Services, US Government
contact email	machnerm@mail.nih.gov
lab head
David Anderson
contact affiliation	NIH/NIDDK
contact email	davida@mail.nih.gov
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD037059
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD037059

PRIDE project URI

Repository Record List

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